Welcome to the Current Issue of the Journal of Comprehensive Research in Cancer Nursing (JCRCN). This issue highlights cutting-edge research and innovative practices in nursing informatics and healthcare technology, focusing on advancing patient care, improving workflows, and enhancing decision-making processes.
Featured Articles in the Latest Issue
- Volume 2 (Issue 1) JANUARY- JUNE 2026
Research Articles
Impact of Nurse-Directed Symptom Cluster Interventions in Advanced Breast Cancer Chemotherapy Patients
Vol.2(1); Pages:1-11. Published on February 2026
Abstract
Clusters of symptoms, including fatigue, nausea, pain, and sleep disorders, are common in the population of patients with advanced breast cancer under chemotherapy, which seriously impairs the quality of life and the adherence to the treatment. This was a randomized controlled trial which examined the feasibility of an intervention based on symptoms cluster leadership by nurses versus the conventional oncological care. One hundred and eighty patients of two tertiary cancer centers were selected randomly to be assigned to an intervention group and receive structured weekly nursing evaluations, symptom-specific action plans, and telephonic follow-ups, or to a control group, who received normal care. The severity of the symptoms and interference was assessed with the validated patient-reported outcome measures in three chemotherapy cycles. It was statistically significant that patients in the intervention group showed statistically significant composite symptom clusters reduction scores and functional status improvement than controls (p < 0.01). On top of that, the number of unplanned visits to the hospital decreased by 18 percent among the intervention group. Results highlight the importance of specialized oncology nurses to actively detect and treat the interrelated symptoms. The implementation of structured symptom cluster protocols with nurses in the conventional oncology practice can promote patient-centered outcomes and resource optimization in the treatment of breast cancer of the third phase.
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Impact of Oncology Nurse Navigation on Treatment Adherence in Patients with Colorectal Cancer
Vol.2(1); Pages:12-20. Published on February 2026
Abstract
Adherence to treatment is another important outcome determinant in the management of colorectal cancer. This prospective cohort trial was a study that investigated the impact of oncology nurse navigation on chemotherapy and follow-up attendance among 210 patients with newly diagnosed stage II-III colorectal cancer. Two academic cancer centers were used to evaluate the participants and they were followed in six months. Structured nurse navigation which comprised of care coordination, appointment reminders, psychosocial assessment, and education on the adverse effects of treatment were provided to the intervention group. The comparison group was provided with the traditional multidisciplinary oncology care without specific navigation services. Compliance rates, appointment non-attendance as well as dose adjustments were documented and compared. Patients assisted by nurse navigators had 22 percent completion rates of scheduled rounds of chemotherapy and a much lower instance of missed appointments (p < 0.05). Moreover, the level of patient satisfaction and continuity of care were much higher in the navigation group. The results demonstrate the critical nature of oncology nurses in reducing communication gaps, eliminating obstacles to treatment, and encouraging patients to continue using cancer care pathways. Colorectal oncology environments can be improved in terms of clinical and experiential outcomes through the implementation of structured nurse navigation programs.
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Exploring Psychological Distress and Coping Experiences in Hematologic Malignancy Transplant Patients
Vol.2(1); Pages:21-29. Published on March 2026
Abstract
Patients receiving hematopoietic stem cell transplantation in managing hematologic malignancies encounter a significant amount of psychological distress because of the severity of the treatment, extended hospitalization, and lack of prognosis. This analytic cross sectional evaluation examined the state of anxiety, depression and coping mechanisms in 145 adult transplant patients in special transplant units. Validated distress and coping scales were used as standardized instruments and administered at the peri-transplant period. Clinically significant anxiety (48%), and depressive symptoms (37%), were found to be high. Lower distress scores were found to be correlated with problem-oriented coping strategies and higher rates of psychological morbidity were correlated with avoidance based coping (p < 0.01). Multivariate regression analysis showed that the effects of social support and structured nurse-led counseling had a significant moderating effect on the outcomes of distress. The findings highlight the fact that oncology nurses play a critical role in the initial psychological screening and supportive interventions during the process of transplantation. Evidence-based psychosocial nursing protocol development can potentially minimize the effects of emotional burden, increase resilience and broaden the overall recovery patterns of patients receiving stem cell transplantation in the treatment of hematologic cancers.
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Evaluation of a Nurse-Delivered Palliative Care Education Program for Family Caregivers of Lung Cancer Patients
Vol.2(1); Pages:30-40. Published on March 2026
Abstract
Patients with advanced lung cancer often cause emotional stress, caregiving pressure, and insufficient symptom management preparation to their caregivers. This quasi-experimental intervention study assessed the efficacy of an education program based on a structured nurse-delivered palliative care education program on 120 caregivers who were recruited in two oncology facilities. The intervention included four sessions that were taken once per week and were devoted to the recognition of the symptoms, management of medicine, communication strategies, and self-care methods. Validated scales were used to measure caregiver burden, preparedness, and quality-of-life indicators before and after the intervention. According to the participants who were provided with the educational program, caregiver burden scores and confidence in managing dyspnea, pain, and fatigue were significantly reduced in comparison with the baseline scores (p < 0.05). Moreover, there was an enhanced communication between the caregivers and their patients. The results indicate that oncology nurses can have a crucial role in empowering family caregivers with the help of specific educational interventions. Incorporation of structured palliative education programs into the regular oncology services could increase the well-being of caregivers and lead to the improved patient-centered palliative outcomes.
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Implementation of Digital Health Monitoring by Oncology Nurses to Reduce Chemotherapy-Related Complications
Vol.2(1); Pages:41-49. Published on April 2026
Abstract
Oncology nurses can use digital health technologies to offer new opportunities and monitor the patients who have undergone outpatient chemotherapy and identify early complications. This implementation study was a mixed-methods design where evaluation was done on a nurse-managed remote monitoring system in a study of 160 adult cancer patients receiving systemic treatment. The patients were provided with the daily symptom reports via a secure mobile application that produced automated warnings analyzed by oncology nurses. The quantitative measures were emergency department visits, hospital admissions, and the severity of reported adverse events after a period of three months. Qualitative interviews were carried out in order to investigate the experiences of nurses and patients in terms of system integration. These findings showed a 25 percent decrease in the number of emergency visits and the promptness of neutropenic symptoms compared to the historical controls. Both the nurses and patients said that the usability was high, along with the perceived benefit of safety. Issues such as alert fatigue and a requirement to adapt to workflow were a challenge. The article confirms the viability and applicability of digital monitoring systems that are led by nurses. Integrating organized digital surveillance measures into the nursing practice in the field of oncology can minimize the likelihood of complications and enhance the continuum of care in the chemotherapy process of patients.
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