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- Volume 1(Issue 1) JANUARY- JUNE 2025
Research Articles
Emerging Perspectives on Plumbago zeylanica: Combatting Antimicrobial Resistance and Exploring Therapeutic Potentials
Vol.1(1); Pages:1-8. Published on June-2025
Abstract
For many centuries, Plumbago zeylanica which is also referred to as Chitraka, has been significant in Ayurveda because of its numerous medical uses. The review reviews the phytopharmacological actions of P. zeylanica and its beneficial compounds, pointing out its strong potential in addressing antibiotic resistance by employing plasmid curing. Some important secondary metabolites (plumbagin and lawsone) present in this plant show good antimicrobial, antioxidant, anti-inflammatory, anticancer, antidiabetic and leishmanicidal effects. Since there is a global concern about multidrug-resistant bacteria, the power of P. zeylanica extracts to eliminate resistanceproviding plasmids is a safe and new way to restore the effectiveness of available antibiotics. This review combines research from the past with recent science to show that P. zeylanica carries important benefits for both integrative and preventive medicine.
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A Synergistic Herbal Preparation from Ayurveda for Kidney Dysfunction
Vol.1(1); Pages:9-17. Published on June-2025
Abstract
If we talk about Chronic Kidney Disease (CKD), it involves lasting problems in the kidneys which may include reduced nephron function and higher risk of heart disease. Punarnavadi Kwath contains nine classical Ayurvedic herbs such as Boerhavia diffusa, Berberis aristata, Curcuma longa, Zingiber officinale, Terminalia chebula, Tinospora cordifolia, Plumbago zeylanica, Clerodendrum serratum and Cedrus deodara. Their antiinflammatory, diuretic, antioxidant and nephroprotective features assist in reducing the issues like inflammation, watery legs and high levels of serum creatinine and urea in people with CKD. The review brings together information on how each ingredient affects the body through studies and clinical experiments. It also points out the therapeutic value, safety and the right use of Punarnavadi Kwath for treating CKD and putting off the need for dialysis or renal transplantation..
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Fixed Dose Combinations as a Paradigm for Enhancing Therapeutic Efficiency: A Comprehensive Overview
Vol.1(1); Pages:18-25. Published on June-2025
Abstract
Through the use of FDCs, the administration of multiple active ingredients is possible in just one dosage form to aid in achieving the best treatment results. It investigates the key ideas, clinical applications and how FDCs are used to increase treatments’ results, patient commitment and save money, especially for chronic or comorbid illnesses. This paper highlights the key importance of FDCs by explaining how formulation, regulations and personalized medicine issues affect them. The review mentions interesting design strategies and talks about new ways FDCs could have an impact on global healthcare.
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Holistic Ayurvedic Intervention in Childhood Bronchial Asthma: Evidence from an Individual Case Report
Vol.1(1); Pages:26-33. Published on June-2025
Abstract
Tamaka Shwasa is also called bronchial asthma and is described as a chronic disease with frequent breathlessness, wheezing and cough. In Ayurveda, it is counted as a kind of Shwasa Roga and typically makes managing children’s cases difficult and requires repeated care. This case is of a 7-year-old male child diagnosed with Tamaka Shwasa. Doctors followed an Ayurvedic method in treating the child by giving herbs and adjusting lifestyle choices to help balance the aggravated doshas. People reported improved symptoms including difficulty in breathing, coughing fits and restless sleep. Through this case, it is clear that Ayurveda may offer children with asthma a better and healthier alternative to standard treatments.
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Pharmacological and Toxicological Duality of Helleborus Species: Therapeutic Potential Versus Cardiotoxic Risk
Vol.1(1); Pages:34-41. Published on June-2025
Abstract
The Helleborus genus which is part of the Ranunculaceae family, includes plants that have been used in the past for their strong pharmacological and poisonous qualities. This report will focus on studying traditional uses, the plant’s chemical components and the potential medical effects of different Helleborus species, especially Helleborus odorus Waldst. et Kit. Active compounds in a plant’s roots and their roles in several therapeutic actions, are emphasized. Among these are activities such as increasing heart power, strengthening the immune system, fighting against bacteria, fighting tumors, helping the body eliminate excess fluids and causing vomiting. The pharmacological importance of Helleborus is shown by its secondary metabolites such as bufadienolides, flavonoids and phenolic glycosides. Even though they can be used for medical purposes, these plants are quite toxic, so they must be handled with care in drugs. All in all, Helleborus plants are significant and complicated tools used in the field of pharmacology.
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