Welcome to the Current Issues section of JPDST. This page offers access to the latest research and previously published volumes that explore cutting-edge developments in pharmaceutical devices, smart drug delivery systems, digital therapeutics, and allied disciplines.
Featured Articles in the Latest Issue
- Volume 1 (Issue 2) JULY– DECEMBER 2025
Research Articles
Empowering Pharmacy Students with Real-World Skills
Vol.1(2); Pages:1-8. Published on July-2025
Abstract
Pharmacist scope has drastically changed, which has led to the shift in pharmacy education to competency-based models. GIMMICS® is an educational game (serious game) and simulation designed at the University of Groningen that provides a unique environment to practice key professional competencies in a realistic and highly motivating setting that combines real-life situations with competitive features. The paper lists the objectives, evaluation techniques, teaching techniques and perceptions of students playing the GIMMICS game. Skills in communication, collaboration, leadership, and pharmaceutical expertise will be improved because the game will simulate daily activities in a community pharmacy. The students participate in various activities, including counseling patients and managing prescriptions, and interprofessional collaboration. They are assessed as individuals and in pharmacy teams, and success in the game is determined by the flow of patients. The simulation is already implemented in a number of universities around the world and students responded well to it due to the realistic and interactive learning experience.
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Design and Assessment of a Smart Inhaler with Bluetooth Connectivity for Real-Time Asthma Monitoring and Management
Vol.1(2); Pages:9-19. Published on July-2025
Abstract
This paper is a description of a Bluetooth-enabled smart inhaler which was designed, developed and clinically tested in an attempt to enhance the management of asthma. The device also captures usage patterns, inhalation technique, and environmental triggers provides real-time feedback and adherence reminders over a mobile app. Usability testing, over an 8-week period with 60 asthma patients (aged 1855), showed a notable 25-percent improvement in proper inhaler use (p < 0.001) and a 30-percent jump in medication compliance. There was a high patient satisfaction, 89% showed an interest to continue using it. The evidence indicates that the use of smart inhalers with Bluetooth technology has a significant effect as it improves inhaler technics, adherence, and patient engagement, which may lead to the diminution of asthma exacerbations and the overall healthcare costs.
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Wearable Transdermal Drug Delivery Patch with Controlled Release of Micro-Needles to Management of Chronic Pain
Vol.1(2); Pages:20-28. Published on July-2025
Abstract
This paper presents the progress and pre-clinical testing of a wearable transdermal drug delivery patch containing micro-needle array and an electronically controlled release capability to treat chronic pain. The patch works with buprenorphine and consists of a pliable polymeric base, to enhance skin adherence, and a programmable controller with the dosage varying over a 72-hour interval. Preclinical trials on skin models using porcine skin proved a micro-needle insertion success rate of 95% or above on skin, with little irritation and no major tissue damage. The steady-state concentration of drugs was reached in the controlled release within 4 hours, stabilized during the application process. Fine mechanical strength and comfort to the user were also present in the device. These findings indicate a large potential impact in terms of enhancing adherence, improving the dosing frequency, and patient outcome in the long-term pain treatment.
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Smart Global Active Insulin Pen featuring embedded dose-tracking and hypoglycemia alert A 6-month clinical trial
Vol.1(2); Pages:29-38. Published on August-2025
Abstract
This was a six-month prospective clinical study evaluating the effects of a smart insulin pen with automated dose tracking, injection reminders, and Bluetooth- enabled hypoglycemia alerts with a smartphone application. Three outpatient clinics provided a total of 110 adult patients with either type 1 or 2 diabetes. The main outcome measures were the levels of HbA1c, adherence to medication, the incidences of hypoglycemia and patient satisfaction. The smart pen did keep track of all insulin injections automatically, synched with blood sugar readings and produced predictive alerts to help avoid hypoglycemia. The obtained results indicate a prominent mean reduction in HbA1c levels of 0.8% (p < 0.01), 23% increase in adherence rates, and 15% decline in selfreported incidences of hypoglycemia. Over 90 percent of the customers who responded to the use of the device gave it high ratings as being of great help in controlling the diabetes. These data demonstrate the possibility of smart insulin pens in their role to enhance glycemic control, therapy adherence, and patient safety management of diabetes in everyday practice.
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The Design, fabrication, and dissolving performance of 3D-Printed Personalized oral drug delivery devices in children patients
Vol.1(2); Pages:39-47. Published on August-2025
Abstract
This paper discusses the research trend on the 3-D printed oral drug delivery device that will be purposefully designed to accommodate the pediatric population to overcome flexibility, adherence, and treatment customization issues inherent to the disease. Fused deposition modeling (FDM) was applied in both formulation of a placebo and a paracetamol-loaded formulation in several child-friendly shapes, colors, and flavor. Functionality was characterized by mechanical integrity, uniformity of dose administration and solubility. It was demonstrated that the geometry of the devices could play a significant role in the drug release rates, which had to be able to deliver specific therapeutics. The content of paracetamol was evenly divided among the samples and the controlled release was found in certain designs up to 60 minutes by a dissolution study. Caregiver and pediatrician acceptability testing showed a high rate of acceptance of the visual acceptability and potential increased patient compliance. Such results indicate that 3D printing can be successfully utilised in the pediatric prescription-drug delivery context offering a new variant of dose customisation, better taste acceptance and patient involvement in the pediatric drug treatment process.
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