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Volume 1
Issue 2 JULY– DECEMBER 2025
Volume 1 (Issue 2) JULY– DECEMBER 2025 Research Articles
Reviving Ancient Remedies: Botanical Knowledge and Medical Practices Across Cultures in the Age of Discovery
Vol.1(2); Pages:1-8. Published on July-2025
Abstract
This research paper will cover the revolutionary era in the history of medicinal botany between the time Columbus first voyaged in 1492, and the middle of the seventeenth century. It follows the changing knowledge of therapeutic plants in Europe, influenced by the rediscovery of classical Greek works, the re-evaluation of Arabic and mediaeval pharmaceutical tradition and the addition of newcomics flowers of the Americas. The article notes the transformation of textual philology to empirical botanical determination and institutionalizing botanical gardens as teaching institutions. It also looks at how well New World plant knowledge was absorbed or repelled by European medical systems, providing anWARE.
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Curcumin as an adjunct to antidepressant therapies in major depression: randomized, double-blind, placebo-controlled trial
Vol.1(2); Pages:9-19. Published on August-2025
Abstract
Curcuma longa, a poly-phenolised compound with demonstrated neuroprotective, anti-inflammatory effects has the potential to safeguard depressive disorders. It was a double-blind, placebo-controlled clinical trial assessing the superiority of curcumin supplementation to a standard antidepressant treatment in adults with moderate- or severe forms of major depression disorder (MDD). One hundred and twenty participants were randomized to either a group taking 500 mg of curcumin twice a day, a group taking the placebo, and in addition, their usual selective serotonin reuptake inhibitors (SSRI) for an 8-week trial. The most important outcome was the change in Hamilton Depression Rating Scale (HAM-D) scores, Beck Depression InventoryII (BDI-II), serum inflammatory biomarkers (CRP, IL-6) were measured. The curcumin group showed a much larger decrease in HAM-D scores ( -11.3 vs -7.4, p < 0.01) and BDI-II scores ( -12.7 vs -8.5, p < 0.01), at week 8 than placebo. The amount of lowering of the inflammatory markers was stronger in the curcumin group. The evidence that the study provides substantiates the position of curcumin as a useful and safe pharmacotherapy supplement in MDD, which is worth taking into account in the context of integrative therapeutic plans.
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Ashwagandha Root Extract Does not Relieve Fatigue Caused by Chemotherapy: a Randomized Trial
Vol.1(2); Pages:20-30. Published on September-2025
Abstract
The effects of chemotherapy-induced fatigue (CIF) are among the most disabling outcomes of cancer treatment that remarkably influence the quality of life and adherence to the treatments. Ashwagandha (Withania somnifera) root extract with adaptogenic effects can assist with fatigue so as well as contribute to general wellbeing. In this randomized controlled trial, standardized ashwagandha root extract (at a dose of 600 mg/day) was assessed in terms of effectiveness and security in the control of CIF in chemo-treated patients with cancerous complaints of adult age. One hundred people were randomly assigned the use of ashwagandha extract or placebo in 8-weeks, both being accompanied with regular oncologic treatment. The beta cell fatigue scale was measured with the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) scale, and further indicators were the quality of life and serum cortisol concentrations. The findings were that the ashwagandha group had significantly higher increase on FACIT-F scores (+9.4 vs +3.1, p < 0.001) and also exhibited significant decreases in serum cortisol levels in comparison with the placebo sugar pill. There were no serious adverse events. The evidence indicates that ashwagandha supplement could be an effective and secure integrative treatment on CIF in cancer patients.
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Blending of Omega-3 Fatty Oils and Statin Therapy in Hyperlipidemia: A Multicentric Integrative Route
Vol.1(2); Pages:31-40. Published on October-2025
Abstract
The prevalence of hyperlipidemia still continues to be a major risk factor when it comes to cardiovascular diseases, regardless of the statin use. In this multicenter prospective interventional study, the authors intended to examine the effect of an oceanic combination of omega-3 fatty acids (2 g/day) with statin therapy in a population of patients with refractory hypertriglyceridemia. As conducted in three tertiary care facilities in Lebanon, Sweden, and Norway, 180 patients were enrolled in the study with 12 weeks of randomization into either a combination therapy group or statin-only group. The key measure was the change in proportion of serum triglycerides and secondary measures were LDL-C, HDL-C, high-sensitivity C reactive protein (hs-CRP) and adverse events pattern. Combination therapy led to 26.7 percent decrease of triglycerides, 10.8 percent in control group (p < 0.001). There were also increases in the levels of HDL-C and hs-CRP. Major safety considerations were not cited. The two findings corroborate the idea of combining omega- 3 supplementation with statin medication as an effective measure of ensuring that the lipid levels of the hyperlipidemic patients are optimized.
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A Randomized Double-blind Trial of Bacopa monnieri with Cognitive Training in Mild Cognitive Impairment
Vol.1(2); Pages:41-51. Published on November-2025
Abstract
MCI is a potentially progressive condition with severe consequences into the older age and in need of effective interventions on the basis of adjunctive therapies to prevent cognitive degradation. This randomized and placebo-controlled design, involving a double-blind design trial was aimed to evaluate the safety and efficacy of standardized Bacopa monnieri extract 300 mg daily combined with a structured and originally designed intense 12-week computerized cognitive endpoint aim at reducing the amnesia state in the amnestic MCI patients aged between 60-79 years. Two hundred of them were randomized into BM-Std + training versus placebo + training groups. The major outcomes were ADAS-Cog and memory composite scores. Secondary outcomes measured executive function, quality of life, biomarkers of oxidative stress (MDA) and brain derived neurotrophic factor (BDNF). Significantly improved ADAS-Cog ( p < 0.001) and memory composite (p = 0.002) were observed in BM-Std group (minus 3.5 points and minus 1.6 points respectively) compared with placebo. Analysis of biomarkers showed a decrease of MDA and increase of BDNF in the treatment arm (p < 0.05) which demonstrates a neuroprotective effect. Side effects were mild and similar among the groups and most were gastrointestinal distress. Bacopa monnieri and cognitive training was well tolerated and produced clinically meaningful cognitive improvements. Greater, longitudinal studies should be conducted to determine whether these effects are lasting and whether the outcomes could prevent further dementia occurrence.
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Issue 1 JANUARY- JUNE 2025
Volume 1(Issue 1) JANUARY- JUNE 2025 Research Articles
Improving Patient Empathy Modeling for Compassionate Care of the Underserved by Pharmacy Students
Vol.1(1); Pages:1-9. Published on May-2025
Abstract
The study aims to see if the PEM training program alters pharmacy students’ attitudes toward groups facing hardships during advanced experiential learning.Students involved in advanced rotations at two primary care facilities for underserved patients worked on a PEM assignment for 10 days. All participants played the role of a patient with several chronic diseases who faced various challenges related to accessing healthcare. Each learner took the Jefferson Scale of Physician Empathy (JSPE) pre/post our session and also reflected daily and wrote papers on their experiences.Twenty-six pharmacy students undertook the PEM exercise in 2005-2006. The students had higher JSPE scores after receiving the intervention. Analysis of student reflections indicated that they recognized the difficulties of taking medications, greatly sympathized with a diversity of patients facing health and social difficulties and gained ability to address these challenges in their professional work.The PEM approach allowed pharmacy students to show more empathy towards underserved patients. I was able to test what I had learned immediately in the real-life scenarios found during advanced practice rotations.
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Developing and Assessing the Effects of a Pharmacy Graduate-Level Health Services Research Methods Course
Vol.1(1); Pages:10-16. Published on May-2025
Abstract
This paper gives a clear summary and analysis of the Health Services Research Methods graduate course taught at the University of Arizona R. Ken Coit College of Pharmacy. In this interactive and discussion-based course, students gain key knowledge about developing research in healthcare and how to review research methods. Performance by students is measured through written tests, making original research proposals and ongoing lowamount tasks. In five years, twenty-seven graduate students have finished this course. Most students have responded positively and suggested only a few things to make it better. Reviewing a course on pharmacy graduate research reveals that most students liked it and gives suggestions for changing or improving the course and idea for similar courses.
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Strategies and Best Practices for Improving Interprofessional Team Based Care Models in Community Pharmacies
Vol.1(1); Pages:17-24. Published on May-2025
Abstract
People are increasingly viewing community pharmacies as places for health services other than getting drugs. Community pharmacists must collaborate more often with healthcare workers as delivery of community-based care has become more complex. It is necessary, therefore, to describe best ways and recommendations that help stakeholders react to the changing environment and benefit patients more. The white paper presents examples of interprofessional practice where community pharmacies are involved around the world and afterward, changes the popular guiding principles for interprofessional practice to fit the needs of community pharmacy. Thus, this theory underlines that patients should be placed at the core of team-based care, leadership teams should demonstrate support for cooperation between providers, an interprofessional system should be built including community pharmacists, respect for community pharmacy should be upheld, gaps in communication and technology should be addressed and lastly, community pharmacies should join in on interprofessional learning. Handling problems and taking advantage of new opportunities is necessary to support practice transformation and reinforce community-based pharmacists’ role in working with other health professionals.
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Views of Pharmacy Students Regarding the Use of Tea Tree Oil, Aloe Vera, Lavender, and Calendula as Herbal Treatments for Acne
Vol.1(1); Pages:25-32. Published on May-2025
Abstract
When oil and dead skin clog the hair follicles, it causes skin acne. In this research, the effects of tea tree oil, aloe vera, lavender and calendula on acne were studied while exploring the opinions of pharmacy students about them. There were 5 questions that focused on knowledge and 5 on opinions, about natural ways to treat acne in the survey. Out of the 39 participants involved (10 males and 29 females), every person answered the demographic questions. However, 34 students (87%) filled out the section on knowledge and opinions. The success rate for knowledge-related questions was 75.9% and each question had an accuracy from 14.7% to 97.1%. Most respondents supported herbal treatments for acne and by a wide margin, agreeing that they do indeed provide relief. Remarkable is that over half of those surveyed strongly supported the benefits of lavender for unwinding and alleviating stress. As a result of this investigation, it is clear that including evidence-based complimentary approaches on acne management could be advantageous for both students and practitioners of pharmacy.
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Advancing Inclusive Practices Addressing Normative Biases in UK Pharmacy Education through Queer-Affirming Reforms
Vol.1(1); Pages:33-40. Published on May-2025
Abstract
Using queer pedagogy, this study reviews UK pharmacy education courses for assumptions that favor heteronormative and cisnormative beliefs. Both the curriculum goals of course leads and the daily experiences of students in the 25 MPharm programs were explored and compared through surveys. Analysis has shown that attending to heterosexual and cisgender identities is normal practice in most pharmacy classrooms, reflected by the responses of 61.1% of educators and 71.3% of students. This indicates that pharmacy education shows more opposition than support to LGBTQI+ people, as it mainly discusses LGBTQI+ health concerns in negative contexts. Even though the topic of LGBTQI+ rights is rarely discussed in class, students are asking, questioning and fighting the common beliefs related to sexual orientation and gender in education. The study provides a way to study traditional views in health professions education and encourages changes that end practices related to heteronormativity, preparing graduates to care for all patients.
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