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Many people taking antihypertension medication fail to follow the recommended dosages, a situation that results in more heart problems and higher medical expenses. Following the prescriptions given by doctors is very important for lowering high blood pressure risks. Medication synchronization is an approach that simplifies picking up drugs by arranging each person’s refill schedule on the same date. Although other studies show that synchronization helps patients stick to their medication, there is not enough proof to judge its effects on blood pressure. This study’s goal is to examine if patients who take part in a medication synchronization program supervised by pharmacists have better control of their blood pressure. Design: The researchers will use a prospective, longitudinal cohort design and look at how the blood pressure of two groups compared: one which receives medication synchronization and one which follows regular medication pick-up processes. To participate, patients have to take at least two antihypertensive medicines and should have gone to the pharmacy for six months straight to get their prescriptions filled. Blood pressure will be measured in research subjects for 10 months after the beginning of the study. Analyses that use inverse-probability-oftreatment weighting will take care of any confounding factors and missing data present in the data.As of the time of writing, enrolling patients is almost done, while their last blood pressure readings and medication reports are being collected. Data analysis will be carried out once every patient visit is finished.At the end, the protocol describes research targeting a relationship between medication synchronization and results for people with hypertension. Based on the findings, it will be decided whether a future randomized controlled trial is needed to check how much this intervention helps blood pressure and heart health.